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Peptide Development Platform

Apeloa Peptide Development Platform offers comprehensive services from peptide lead optimization to commercial manufacturing. With over 20 years of experience in peptide CMC (Chemistry, Manufacturing and Controls), the platform specializes in solid-phase peptide synthesis (SPPS), liquid-phase peptide synthesis (LPPS), and hybrid peptide synthesis methods for linear, cyclic, and modified peptides. The platform's expertise extends to peptide drug conjugates (PDCs), radionuclide drug conjugates (RDCs), and the synthesis of unnatural amino acids and linkers. Apeloa's state-of-the-art facilities and dedicated team ensure high quality and efficient peptide process development and manufacturing.

20 ⁺

years of experience in peptide CMC
35 ⁺

dedicated peptide R&D scientists

Team

Apeloa Peptide Development Platform is led by a team of highly experienced professionals, including 35 dedicated peptide R&D scientists. With a combined expertise of over 20 years in peptide CMC, the team has extensive experience in peptide drug development, successf

Services

The Peptide Development Platform committed to providing comprehensive, end-to-end services for peptide drug development at all stages, from early research, clinical phases, to commercialization, enabling more efficient and compliant peptide drug development for partners. Focuses on the research, development, and manufacturing services related to peptide drugs, including: ● Development and production of unnatural amino acids, pseudoproline dipeptides, conjugation linkers, peptide intermediates, linear peptides, cyclic peptides, and modified peptides ● Development, transfer, and validation of synthetic processes and analytical methods ● GMP manufacturing, stability studies, and preparation of regulatory submission documents

Equipment

● Solid-phase synthesis reactors: 100 mL - 5 L for R&D, 30 L-500 L for scale-up production ● Liquid-phase synthesis reactors: 100 mL - 50 L for R&D, 100 L - 8000 L for scale-up production ● Preparative HPLC systems: DAC 50, DAC 100, DAC 300, DAC 600 ● Nano-filtration systems: NF 1812, NF 2540, NF 4040, NF 8040 ● Lyophilizers: Flask lyophilizers and tray lyophilizers (1 m2 - 20 m2)

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